Despite years of anarchy following the New Mutation, Africa has regenerated itself under the oft-brutal but relatively efficient Azanian (former South African) and Congolese allied governments, who together have melded many of Africa's former warring statelets into a loose federation. The secret of Congo's success has been in carving its territories into separate ethnic provinces where one ethnic group is a majority by more than 95%. This regime of ethnic cleansing has resulted in fewer civil wars and more cooperation among the various tribes, while still allowing each to operate under a single banner. After the bloodletting of conquest and disease had subsided, most Central African nations were relieved of the burden of overpopulation which had caused so many previous conflicts. Free trade agreements with North America and Pacifica under the auspices of Protocol allowed Congo and Azania to develop budding industrial enterprises, which in turn attracted corporations who had few sources of cheap labour left in the world. Heavy industry developed slowly and painfully, but with Neo/Victorian investment in Congo in 2030 the money for base- and infrastructure- building became available. Congo and Azania became bitter rivals, with Azania already having swallowed most of southern Africa. Yet for all it's conquests, Azania still tolerates the autonomous Republics of Orangeria (Afrikaners), The Cape (English/Mixed), and Swaziland (Zulu).

The New Mutation also brought ecological disaster and, much later, ecological regeneration. Africa is one of the few places on Earth authorized by the Medical Collegium to experiment with genegineering technology. Many high-tech labs have relocated to Uganda and Congo to field test Clotis creatures, new strains of super-bacteria, and even forbidden parasites. Super-endurant algae are being used to stabilize and moisturize the migrating sands of the Sahel, while mercenary troops combat rebels using clonal chimerics.

Uganda, Tanzania and Kenya have become Africa's success stories. Their high investment in education, tax incentives for mid-tech export corporations, commitment to open economies, and good treatment of foreign corporations attracted a wave of investment seeking a haven from troubled Asia during the 'Tens'. Today Uganda is a 'newly-developed' nation, brimming with heavy industry and even some space development corporations. Kenya, despite its problems with providing basic services to a huge population, has managed to grow at a rapid pace. Tanzania devolved power to its many provinces in 2025, and proposed an initiative to bind the three countries into a regional grouping of over 120m people. Today these three are heavily linked in a military alliance against Congo as well as a customs union. The region has a heavy presence of Intercontinentals, as well as several large indigenous corps such as Baklan Processing and Dushambe Motor Industries.